WebMar 27, 2012 · Objective GTP cyclohydrolase I (GCH1) is the rate-limiting enzyme for tetrahydrobiopterin biosynthesis and has been shown to be a promising therapeutic target in ischemic heart disease, hypertension, atherosclerosis and diabetes. The endogenous GCH1-interacting partners have not been identified. Here, we determined endogenous … WebNov 26, 2009 · The first group contains two chaperones and two transcription factors. The second group of modifiers include chaperones (DNJA1), several components of the ubiquitin–proteasome system, including Carboxyl Terminus of HSP70-interacting protein (CHIP), and genes involved in signal transduction, RNA metabolism and apoptosis.
유비퀴틴 - 위키백과, 우리 모두의 백과사전
WebOct 31, 2024 · Cancers are frequently addicted to oncogenic missense mutant p53 (mutp53). DNAJA1, a member of heat shock protein 40 (HSP40), also known as J … WebDNAJA1 and DnaK (PDB entries 2m6y and 2qwo) The structure of DnaK (red, with a bound nucleotide in magenta) with the J-domain of auxilin (blue) was solved by engineering a … thd64.fr
DNAJA1 and Pancreatic Cancer - RCSB: PDB-101
WebPlease cite: Sebastian Canzler, Markus Fischer, David Ulbrecht, Nikola Ristic, Peter W Hildebrand, René Staritzbichler: ProteinPrompt: a webserver for predicting protein-protein interactions, bioRxiv 2024.09.03.458859 ProteinPrompt is free for non-commercial users WebAug 6, 2024 · The cochaperone protein DNAJA1 (HSP40) is downregulated four-fold in pancreatic cancer cells. The impact of DNAJA1 expression on pancreatic ductal … • Oh S, Iwahori A, Kato S (1993). "Human cDNA encoding DnaJ protein homologue". Biochim. Biophys. Acta. 1174 (1): 114–6. doi:10.1016/0167-4781(93)90104-l. PMID 8334161. • Kanazawa M, Terada K, Kato S, Mori M (1997). "HSDJ, a human homolog of DnaJ, is farnesylated and is involved in protein import into mitochondria". J. Biochem. 121 (5): 890–5. doi:10.1093/oxfordjournals.jbchem.a021670. PMID 9192730. thd65