Web26 de fev. de 2024 · HIF1α-dependent glycolysis is associated with pro-inflammatory macrophage differentiation. The glycolytic activities of macrophages were first investigated using different macrophage polarization ... Web15 de set. de 2024 · Hypoxia‑inducible factor‑1α (HIF‑1α) is essential for regulating the osteogenic differentiation of periodontal ligament cells (PDLCs). The regulatory mechanism of HIF‑1α transcription is still not clear. Recently, two long non‑coding RNAs, HIF1A antisense RNA 1 (HIF1A‑AS1) and HIF1A antisense RNA 2 (HIF1A‑AS2), were found to …
Nature丨HIF-1α通路调控软骨细胞成骨的分子机制- X-MOL资讯
Web20 de jun. de 2024 · In this review, we will discuss the current understandings of hypoxia signaling in human diseases by the organ systems, including the heart, lung, liver, and kidney. We will also discuss the ... Web14 de fev. de 2024 · 综上,2024年发表的几篇 关于低氧-乳酸调控在免疫炎症抑制中的突破研究 极大的提高了我们对细胞应答氧气的认识,研究强调了染色质重塑在低氧应答中的重要性,并确定了 乳酸作为糖酵解过程的关 … flowfast terrosso
Frontiers Accumulated ROS Activates HIF-1α-Induced Glycolysis …
WebNational Center for Biotechnology Information WebHIF1A. Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 ( HIF-1) that is encoded by the HIF1A gene. [5] [6] [7] The Nobel Prize in … Web1 de set. de 2024 · Co-transfection of HEK293FT cells with HIF1A-sh-GFP and HIF1α-P2A-RFP plasmids validated the successful shRNA knockdown of HIF1A mRNA by the expression of RFP and GFP reporters, as the HIF1α-P2A-RFP plasmid allows for HIF1α and RFP to be expressed as a single mRNA transcript which is then translated as two … flowfast pumps